Can febrile seizures induced by mental retardation?
Brain injury can cause convulsions, seizures can also cause brain damage. It was proved that once seizures in recent memory there is a transient effect, equivalent to a concussion caused by damage; status epilepticus can cause serious brain damage extent which rendered mental retardation.
Because in the convulsive discharge, the brain tissue of a large number of neurons undergoing rapid, repeated lipid addition to polarization, require more energy to maintain sodium-potassium pump function, neurotransmitter synthesis and release has also increased, to speed up the process of cell metabolism , and convulsions when the body temperature, muscle twitching body metabolism also increase in animal brain metabolic heat can increase by 25%, the energy needed for these activities than the normal 2 to 4 times higher. Abnormal electrical activity of brain seizure discharge itself, namely, the need for energy also increased significantly, which is caused by an important cause of brain damage. Therefore, the largest seizure to the brain caused by the metabolic burden.
Seizures in children with febrile seizures is the most common form, the prognosis is generally good and the incidence of mental retardation caused by very low, it is because the general simple febrile convulsions, seizure frequency of less time is short, quick recovery, no abnormal neurological sign Therefore, when the seizures less impact on the brain. But there are a small number of patients can cause mental retardation, at present there are two interpretations of this, a severe febrile seizures that can cause brain damage, resulting in seizures and mental retardation, which refers to the longer duration of convulsion, convulsions recurrence of the number of The more cerebral injury more likely.
Another view was that, in the febrile seizures before the nervous system is abnormal, this does not occur even in children with febrile seizures mental retardation will also appear, namely, that the sick child with febrile seizures symptoms of the nervous system itself is not the convulsions caused by but in the febrile seizure onset before the febrile seizures and mental retardation is not a causal relationship, but rather common cause of the decision.
Another convulsion caused by brain damage and age are closely related. Infantile convulsion lasted for 30 minutes or more neurons can be produced by ischemic changes, while the adult seizures occurred more than six hours before this change. This is because the brain tissue metabolism in infants and young children during the active nerve cells in the growth, differentiation exuberant period, the developing brain tissue of the most vulnerable, so the earlier age of onset of seizures, the incidence of mental retardation may be higher.
In short, such as febrile seizures have been before the nervous system abnormalities, may lead to future mental retardation, severe seizures can cause brain damage itself affect intelligence.