Ascariasis in children with de-worming treatment

First, de-worming treatment

 (A) benzene imidazole compounds: In order to broad-spectrum insect repellent, can kill roundworm, hookworm and so on. Their insecticidal mechanism of selective drugs on the parasite does not reversibly inhibit the uptake of glucose effect in that the insect endogenous glycogen depletion, and inhibit the fumarate reductase, prevent ATP production, causing parasites can not survive and reproduction, eventually died. Commonly used drugs are:

 1. Mebendazole: a daily dosage for children 50-150mg, for adults per 100mg, sooner or later all times, even for 3 days; if no drive to do, three weeks after the second course of treatment reusable. Effects of the drug piperazine citrate better, side effects rare, a large number of infected insect with this drug, may have abdominal pain, diarrhea, but mild.

 2. Albendazole: Product Name intestinal worms-ching, a new broad-spectrum insect repellent. Dose of 400mg, one to swallow. Efficacy over 90%. But in a large-scale treatment, occasionally occur vomit roundworm response.

 3. Levamisole: the dosage of 150mg, once taking the role of this drug piperazine citrate is less than mebendazole, piperazine is excellent but more side effects mild, occasional nausea, vomiting, anorexia and so on, a small number of patients liver function after medication Light degree of damage. Early pregnancy, liver and kidney disease should be used with caution.

 4. Thiabendazole: Adults per kilogram of body weight 25mg, sooner or later each one plays, and even served three days, Japan and dosage should not exceed 3g, the drug mebendazole has been replaced.

 (B) Pyrantel: (trade name insect spirits, insecticide-ling) is a broad-spectrum insect-resistant drugs, enabling dramatic Ascaris muscle contraction, causing spastic paralysis. Dosage 5-10mg/kg, late 1 ton service. Side effects are headache, dizziness, vomiting in pregnant women, acute hepatitis, nephritis, a serious heart disease and fever patients should suspend the delivery.

 (C) piperazine citrate (piperazine citrate): Adult per 3-4g, per kilogram of body weight per day for children 150mg (the highest amount of no more than 3g) Dayton bedtime clothes, even clothes two days, constipation, diarrhea were added service agent. Side effects of light, occasional dizziness, vomiting, headache and so on. The drug gradually less.

 (D) hard-dong skin: the active ingredient for the TSN. Experiments proved that it can paralysis Ascaris head, so there are certain effects of piperazine citrate, but the amount of large, toxic effects. TSN finished film for the adult 200-250mg, fasting Dayton clothing, this drug is currently little use.

 (E) Other: It has been reported acupuncture oxygen de-worming and de-worming, sometimes with unexpected results.

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